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Acquired Hemophilia: Successfully Treated with Plasma Exchange in a Patient with Hightiter Inhibitors
고농도 항체를 가지는 후천성 혈우병에서 혈장교환술을 이용하여 치료한 1예
The Korean Society of Blood Transfusion 2012;23:68−71
Published online April 30, 2012
© 2012 The Korean Society of Blood Transfusion.

Yu Kyung Kim, Jang Soo Suh
Acquired hemophilia is an extremely rare but life threatening hemorrhagic disease caused by autoantibodies directed coagulation factor VIII. Estimated management guidelines include rapid diagnosis, suppression of bleeding, and elimination of inhibitors by use of immunosuppressants. Plasma exchange is used restrictively as an adjuvant in order to lower the level of inhibitor. We report on a successful therapeutic experience with plasma exchange in a patient with refractory acquired hemophilia. After performance of the plasma exchange procedure, bleeding was controlled and results of coagulation tests showed improvement according to the decrease in levels of factor VIII inhibitor. (Korean J Blood Transfus 2012;23: 14-71)
Keywords : Acquired hemophilia, Factor VIII inhibitor, Plasma exchange

August 2023, 34 (2)
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