The Korean Journal of Blood Transfusion : eISSN 2383-6881 / pISSN 1226-9336

Table. 2.

Table. 2.

Institutional practice, survey, and expert opinion on the titer thresholds of anti-A and -B to determine LTOWB in civilian trauma

Category Source Titer threshold according to the test method (immunoglobulin type if specified)
Saline method Indirect antihuman globulin method Test method not specified
Institutional practice UPMC [13,33] <50 (IgM)
Swedish blood center [14,34,35] <100 (IgM) <400 (IgG)
UCLA Medical Center [36] ≤100
Mayo Clinic [13,27] <200
American Red Cross [20] <200
UT San Antonio [36] <256
UT Houston [36] <256
Survey American adult civilian level 1 trauma centers (n=43) [7] <100 to <256*
American pediatric level 1 trauma centers (n=10) [37] <50 to <256*
International hospitals and air ambulance service (n=37) [12] <50 to <256*,†
Expert opinion Yazer et al. [13] <200 <400
Bahr et al. [14] <100 to <200 (IgM) <250 to <400 (IgG)

*The most common titer threshold for the anti-A and -B in LTOWB was <200 in all three surveys.A hospital in Norway responded to a comment about two requirements for low titer units (IgM titer <250 and IgG titer <500).

Abbreviations: LTOWB, low titer group O whole blood; IgM, Immunoglobulin M; UPMC, University of Pittsburgh Medical Center; UCLA, University of California, Los Angeles; UT, The University of Texas.

Korean J Blood Transfus 2024;35:14-26 https://doi.org/10.17945/kjbt.2024.35.1.14
© 2024 Korean J Blood Transfus