Summary of literatures reported thrombocytopenia in PBSC donors
| Author | Year | Country | Age | Sex | Initial PLT (×109/L) | PHx | Drugs | Injection of G-CSF (days) | Number of apheresis | Lowest PLT (×109/L) | Symptoms with bleeding | Recovery of PLT (days, ×109/L) | Cause of thrombocytopenia | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| U Iltar | 2018 | Turkey | 21 | M | 231 | No | No | 5 | 1 | 19 | No | 15, 255 | G-CSF | [15] |
| X Lu | 2019 | China | 14 | F | 169 | No | No | 6 | 2 | 40 | No | 15, 185 | G-CSF | [5] |
| O Minelli | 2009 | Italy | 51 | M | Normal | No | No | 5 | 2 | 27 | No | 14, 268 | G-CSF | [16] |
| M Tsubokura | 2023 | Japan | NA | F | 157 | No | No | 4 | 1 | NA |
No | NA |
EDTA | [13] |
| SJ Lee | 2023 | Korea | 45 | M | 160 | No | No | 3 | 1 | 23 | No | 15, 401 | G-CSF | This study |
| 60 | F | 202 | No | No | 3 | 2 | 35 | No | 10, 169 | G-CSF | ||||
| 41 | M | 310 |
No | No | 3 | 1 | 79 |
No | 8, 98 |
EDTA, G-CSF |
*Pseudothrombocytopenia. PLT count measured 62×109/L, and platelet aggregation were observed in a peripheral blood smear. After re-evaluation, the PLT count increased to 209×109/L.
†Platelet count with amikacin.
Abbreviations: PBSC, peripheral blood stem cell; PLT, platelet; PHx, past history; G-CSF, granulocyte colony-stimulating factor; NA, not available; EDTA, ethylenediaminetetraacetic acid.