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Analysis of Massive Transfusion Blood Product Use in a Tertiary Care Hospital
일개 3차 의료기관의 대량수혈 혈액 사용 분석
Korean J Blood Transfus 2018;29:253−261
Published online December 31, 2018;
© 2018 The Korean Society of Blood Transfusion.

Young Ae Lim1, Kyoungwon Jung2,3, John Cook-Jong Lee2,3

Department of Laboratory Medicine, Ajou University School of Medicine1, Center of Trauma Surgery, Ajou University Hospital2, Department of Surgery, Ajou University School of Medicine3, Suwon, Korea
아주대학교 의과대학 진단검사의학교실1, 아주대학교병원 외상센터2, 아주대학교 의과대학 외과학교실3
Young Ae Lim
Department of Laboratory Medicine, Ajou University School of Medicine, 164 World cup-ro, Yeongtong-gu, Suwon 16499, Korea
Tel: 82-31-219-5786, Fax: 82-31-219-5778, E-mail:, ORCID:
Received October 12, 2018; Revised November 20, 2018; Accepted December 3, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: A massive blood transfusion (MT) requires significant efforts by the Blood Bank. This study examined blood product use in MT and emergency O Rh Positive red cells (O RBCs) available directly for emergency patients from the Trauma Center in Ajou University Hospital.
Methods: MT was defined as a transfusion of 10 or more RBCs within 24 hours. The extracted data for the total RBCs, fresh frozen plasma (FFP), platelets (PLTs, single donor platelets (SDP) and random platelet concentrates (PC)) issued from Blood Bank between March 2016 and November 2017 from Hospital Information System were reviewed. SDP was considered equivalent to 6 units of PC.
Results: A total of 345 MTs, and 6233/53268 (11.7%) RBCs, 4717/19376 (24.3%) FFP, and 4473/94166 (4.8%) PLTs were used in MT (P<0.001). For the RBC products in MT and non-MT transfusions, 28.0% and 34.1% were group A; 27.1% and 26.0% were group B; 37.3% and 29.7% were group O, and 7.5% and 10.2% were group AB (P<0.001). The ratios of RBC:FFP:PLT use were 1:0.76:0.72 in MT and 1:0.31:1.91 in non-MT (P<0.001). A total of 461 O RBCs were used in 36.2% (125/345) of MT cases and the number of O RBCs transfused per patient ranged from 1 to 18.
Conclusion: RBCs with the O blood group are most used for MT. Ongoing education of clinicians to minimize the overuse of emergency O RBCs in MT is required. A procedure to have thawed plasma readily available in MT appears to be of importance because FFP was used frequently in MT.
Keywords : Massive transfusion, ABO blood group, Emergency


December 2018, 29 (3)
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