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Current Status for Cord Blood Transplantation and Public Cord Blood Bank in Korea
국내 제대혈이식 및 기증제대혈은행 현황
The Korean Society of Blood Transfusion 2013;24:103−110
Published online August 31, 2013
© 2013 The Korean Society of Blood Transfusion.

Sue Shin1,2,3, Eun Youn Roh1,2,3, Jong Hyun Yoon1,2,3
신수1,2,3ㆍ노은연1,2,3ㆍ윤종현1,2,3
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Cord blood is one of the promising sources of hematopoietic stem cell and the public cord blood bank should cryopreserve only high quality, conforming cord blood units for transplantation. Cryopreserved cord blood units have several advantages over other hematopoietic stem cell sources such as bone marrow or mobilized peripheral stem cells; cord blood is in the ready-to-use state after the necessary testing and cause less graft-versus-host disease due to cellular immaturity. The limiting factor is the restricted cell number, which resulted in delayed engraftment and immunologic reconstitution. Selection of cord blood for patients is determined by two criteria: the number of total nucleated cell and the matching of human leukocyte antigen. The cord blood inventory required for any given ethnicity is determined by HLA diversity. In terms of growing interest of cord blood as a stem cell source, we reviewed the current status of cord blood related issues in Korea. (Korean J Blood Transfus 2013;24: 1-110)
Keywords : Cord blood, Public cord blood bank, Inventory, Hematopoietic stem cell transplantation

 

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