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Table. 2.

Table. 2.

Clinical findings of the seven cases with TRALI or possible TRALI

Case NumberSex/ ageDiagnosisSymptoms/ signsRadiologic findingsSupportive treatmentType of component (No. of transfused unit)Time interval before the event*TRALI diagnosis under CCC definitionARDS risk factorsTRALI diagnosis under 2019 new consensus
1F/29Acute appendicitis/Preterm laborDyspnea, nausea/ SpO2 89%Newly developed left pleural effusionNC (7 L/min) → RMPRBC (1)7 mTRALI-1
2F/78AMLDyspnea, fever/ SpO2 88%Multiple faint patchy consolidation in both lungsNC (2 L/min)SDP (2)40 mpTRALISuspected pneumonia2
3M/75HCC/Rectal prolapseChilling, tachycardia/SpO2 73%Bilateral infiltratesNC (3~4 L/min) → IntubationPRBC (1), FFP (3)1 hr 30 mpTRALINoncardiogenic shock2
4F/86DLBCLDyspnea/ SpO2 85%Increased bilateral infiltratesRM (12~15 L/min) + diureticsSDP (2)35 mpTRALIPneumonia2
5M/1ATRTDyspnea/ SpO2 85%Increased multifocal patchy consolidations in both lungsNC (3 L/min) → RM (6 L/min) + dexamethasone → IntubationFiltered PLT (6)35 mpTRALIPneumonia2
6F/39AMLDyspnea, tachycardia/SpO2 85%GGO and consolidation in both lungsNC (2 L/min) → RM (9 L/min) → IntubationSDP (2)3 hr 35 mpTRALIPneumonia2
7M/58Liver cirrhosisDyspnea, tachycardia, fever/ SpO2 94%Aggravated GGO and consolidation in both lungsNC (3 L/min) → RM (5 L/min) + diuretics → IntubationFFP (26), SDP (1)6 hr 10 mTRALI-1

Time interval from the beginning of transfusion to discovered events. Diagnostic criteria include events within 6 hours from the completion of transfusion,

Patient described in table 4 for further investigation.

Abbreviations: CCC, Canadian Consensus Conference; ARDS, acute respiratory distress syndrome; NC, nasal cannula; RM, rebreathing mask; PRBC, packed red blood cell; TRALI, transfusion-related acute lung injury; AML, acute myeloid leukemia; GGO, ground-glass opacity; SDP, single donor platelet; pTRALI, possible transfusion-related acute lung injury; HCC, hepatocellular carcinoma; DLBCL, diffuse large B cell lymphoma; ATRT, atypical teratoid rhabdoid tumor; PLT, platelet concentrate; FFP, fresh frozen plasma.

Korean J Blood Transfus 2019;30:219-29
© 2019 Korean J Blood Transfus