The Korean Journal of Blood Transfusion : eISSN 2383-6881 / pISSN 1226-9336

Table. 1.

Table. 1.

Functions of the ROTEM assays

ROTEM test  Description and interpretation
NATEM Native whole blood sample analyzed following only recalcification.
Impractical for clinical use given long CFT time.
EXTEM Tissue factor activation. Reagent contains tissue factor as an activator and provides information similar to that of the PT.
 APTEM Contains aprotinin for inhibiting fibrinolysis; used in conjunction with EXTEM reagent and compared to EXTEM analysis to assess fibrinolysis.
 FIBTEM Utilizes cytochalasin D, an actin polymerization inhibitor to exclude the platelet contribution.
When compared to EXTEM analysis allows qualitative analysis of the fibrinogen contribution to clot strength.
INTEM Contact activation. Reagent contains phospholipid and ellagic acid as activators and provides information similar to that of the APTT.
 HEPTEM Contains lyophilized heparinase for neutralizing unfractionated heparin; used in conjunction with INTEM reagent and compared to ITEM analysis to assess heparin effect.
Korean J Blood Transfus 2018;29:240-52 https://doi.org/10.17945/kjbt.2018.29.3.240
© 2018 Korean J Blood Transfus